feat: Extend React/Java app to match Lua functionality

Backend:
- Add Pretreatment record for pre-treatment data
- Extend Sample with pretreatment, clinicalExamDate, internalNote
- Extend TherapyRecommendation with detail fields (count, duration, dosage, location)
- Add startvacVaccination and noAntibioticTreatment flags
- Add null-safety defaults for MongoDB compatibility

Frontend:
- Add pretreatment fields to SampleRegistrationPage
- Add special pathogens section to AnamnesisPage
- Add therapy detail pickers to TherapyPage
- Improve AntibiogramPage: full text labels, centered headers
- Fix AdminDashboardPage TypeScript error in chart tooltip

Styling:
- Enlarge matrix buttons for S/I/R text
- Add matrix-col class for centered table columns

backend/src/main/java/de/svencarstensen/muh/domain/Pretreatment.java

@@ -0,0 +1,9 @@
+package de.svencarstensen.muh.domain;
+
+public record Pretreatment(
+        String inUdderInjector,
+        String systemicAntibiotics,
+        String painMedication,
+        String dryOffTreatment
+) {
+}

backend/src/main/java/de/svencarstensen/muh/domain/Sample.java

@@ -3,6 +3,7 @@ package de.svencarstensen.muh.domain;
 import org.springframework.data.annotation.Id;
 import org.springframework.data.mongodb.core.mapping.Document;
 
+import java.time.LocalDate;
 import java.time.LocalDateTime;
 import java.util.List;
 
@@ -29,6 +30,10 @@ public record Sample(
         LocalDateTime completedAt,
         String ownerAccountId,
         String createdByUserCode,
-        String createdByDisplayName
+        String createdByDisplayName,
+        // Additional fields from Lua version
+        Pretreatment pretreatment,
+        LocalDate clinicalExamDate,
+        String internalNote
 ) {
 }

backend/src/main/java/de/svencarstensen/muh/domain/TherapyRecommendation.java

@@ -16,6 +16,15 @@ public record TherapyRecommendation(
         List<String> dryAntibioticKeys,
         List<String> dryAntibioticNames,
         String farmerNote,
-        String internalNote
+        String internalNote,
+        // Additional fields from Lua version
+        String inUdderCount,
+        String inUdderDuration,
+        String systemicCount,
+        String systemicDuration,
+        String systemicDosage,
+        String systemicLocation,
+        Boolean startvacVaccination,
+        Boolean noAntibioticTreatment
 ) {
 }

backend/src/main/java/de/svencarstensen/muh/service/CatalogService.java

@@ -537,7 +537,7 @@ public class CatalogService {
         return toSessionResponse(user);
     }
 
-    public SessionResponse registerCustomer(RegistrationMutation mutation) {
+    public RegistrationResponse registerCustomer(RegistrationMutation mutation) {
         if (isBlank(mutation.companyName())
                 || isBlank(mutation.street())
                 || isBlank(mutation.houseNumber())

backend/src/main/java/de/svencarstensen/muh/service/SampleService.java

@@ -4,6 +4,7 @@ import de.svencarstensen.muh.domain.AntibiogramEntry;
 import de.svencarstensen.muh.domain.AppUser;
 import de.svencarstensen.muh.domain.PathogenCatalogItem;
 import de.svencarstensen.muh.domain.PathogenKind;
+import de.svencarstensen.muh.domain.Pretreatment;
 import de.svencarstensen.muh.domain.QuarterAntibiogram;
 import de.svencarstensen.muh.domain.QuarterFinding;
 import de.svencarstensen.muh.domain.QuarterKey;
@@ -22,6 +23,8 @@ import org.springframework.web.server.ResponseStatusException;
 
 import java.time.LocalDate;
 import java.time.LocalDateTime;
+import java.time.format.DateTimeFormatter;
+import java.time.format.DateTimeParseException;
 import java.util.ArrayList;
 import java.util.Comparator;
 import java.util.HashMap;
@@ -105,6 +108,18 @@ public class SampleService {
                 .orElseThrow(() -> new ResponseStatusException(HttpStatus.BAD_REQUEST, "Landwirt nicht gefunden"));
 
         long sampleNumber = reserveNextSampleNumber(actorId);
+        Pretreatment pretreatment = request.pretreatmentInUdderInjector() == null && 
+                request.pretreatmentSystemicAntibiotics() == null &&
+                request.pretreatmentPainMedication() == null &&
+                request.pretreatmentDryOffTreatment() == null
+                ? null
+                : new Pretreatment(
+                    blankToNull(request.pretreatmentInUdderInjector()),
+                    blankToNull(request.pretreatmentSystemicAntibiotics()),
+                    blankToNull(request.pretreatmentPainMedication()),
+                    blankToNull(request.pretreatmentDryOffTreatment())
+                );
+        
         Sample sample = new Sample(
                 null,
                 sampleNumber,
@@ -127,7 +142,10 @@ public class SampleService {
                 null,
                 authorizationService.accountId(actor),
                 request.userCode(),
-                request.userDisplayName()
+                request.userDisplayName(),
+                pretreatment,
+                parseClinicalExamDate(request.clinicalExamDate()),
+                blankToNull(request.internalNote())
         );
 
         return toDetail(sampleRepository.save(sample));
@@ -144,6 +162,18 @@ public class SampleService {
                 .findFirst()
                 .orElseThrow(() -> new ResponseStatusException(HttpStatus.BAD_REQUEST, "Landwirt nicht gefunden"));
 
+        Pretreatment pretreatment = request.pretreatmentInUdderInjector() == null && 
+                request.pretreatmentSystemicAntibiotics() == null &&
+                request.pretreatmentPainMedication() == null &&
+                request.pretreatmentDryOffTreatment() == null
+                ? existing.pretreatment()
+                : new Pretreatment(
+                    blankToNull(request.pretreatmentInUdderInjector()),
+                    blankToNull(request.pretreatmentSystemicAntibiotics()),
+                    blankToNull(request.pretreatmentPainMedication()),
+                    blankToNull(request.pretreatmentDryOffTreatment())
+                );
+
         Sample saved = sampleRepository.save(new Sample(
                 existing.id(),
                 existing.sampleNumber(),
@@ -166,7 +196,14 @@ public class SampleService {
                 existing.completedAt(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                pretreatment,
+                parseClinicalExamDate(request.clinicalExamDate()) != null 
+                    ? parseClinicalExamDate(request.clinicalExamDate()) 
+                    : existing.clinicalExamDate(),
+                request.internalNote() != null 
+                    ? blankToNull(request.internalNote()) 
+                    : existing.internalNote()
         ));
 
         return toDetail(saved);
@@ -233,7 +270,10 @@ public class SampleService {
                 existing.completedAt(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                existing.pretreatment(),
+                existing.clinicalExamDate(),
+                existing.internalNote()
         ));
         return toDetail(saved);
     }
@@ -324,7 +364,10 @@ public class SampleService {
                 existing.completedAt(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                existing.pretreatment(),
+                existing.clinicalExamDate(),
+                existing.internalNote()
         ));
         return toDetail(saved);
     }
@@ -334,7 +377,7 @@ public class SampleService {
         if (existing.currentStep() == SampleWorkflowStep.COMPLETED) {
             TherapyRecommendation previous = existing.therapyRecommendation();
             TherapyRecommendation updated = previous == null
-                    ? new TherapyRecommendation(false, false, List.of(), List.of(), null, List.of(), List.of(), null, List.of(), List.of(), List.of(), List.of(), null, blankToNull(request.internalNote()))
+                    ? new TherapyRecommendation(false, false, List.of(), List.of(), null, List.of(), List.of(), null, List.of(), List.of(), List.of(), List.of(), null, blankToNull(request.internalNote()), null, null, null, null, null, null, Boolean.FALSE, Boolean.FALSE)
                     : new TherapyRecommendation(
                     previous.continueStarted(),
                     previous.switchTherapy(),
@@ -349,7 +392,15 @@ public class SampleService {
                     previous.dryAntibioticKeys(),
                     previous.dryAntibioticNames(),
                     previous.farmerNote(),
-                    blankToNull(request.internalNote())
+                    blankToNull(request.internalNote()),
+                    previous.inUdderCount(),
+                    previous.inUdderDuration(),
+                    previous.systemicCount(),
+                    previous.systemicDuration(),
+                    previous.systemicDosage(),
+                    previous.systemicLocation(),
+                    previous.startvacVaccination() != null ? previous.startvacVaccination() : Boolean.FALSE,
+                    previous.noAntibioticTreatment() != null ? previous.noAntibioticTreatment() : Boolean.FALSE
             );
             return toDetail(sampleRepository.save(new Sample(
                     existing.id(),
@@ -373,7 +424,10 @@ public class SampleService {
                     existing.completedAt(),
                     existing.ownerAccountId(),
                     existing.createdByUserCode(),
-                    existing.createdByDisplayName()
+                    existing.createdByDisplayName(),
+                    existing.pretreatment(),
+                    existing.clinicalExamDate(),
+                    existing.internalNote()
             )));
         }
 
@@ -396,7 +450,15 @@ public class SampleService {
                 request.dryAntibioticKeys(),
                 resolveMedicationNames(request.dryAntibioticKeys(), medications),
                 blankToNull(request.farmerNote()),
-                blankToNull(request.internalNote())
+                blankToNull(request.internalNote()),
+                blankToNull(request.inUdderCount()),
+                blankToNull(request.inUdderDuration()),
+                blankToNull(request.systemicCount()),
+                blankToNull(request.systemicDuration()),
+                blankToNull(request.systemicDosage()),
+                blankToNull(request.systemicLocation()),
+                request.startvacVaccination(),
+                request.noAntibioticTreatment()
         );
 
         Sample saved = sampleRepository.save(new Sample(
@@ -421,7 +483,10 @@ public class SampleService {
                 LocalDateTime.now(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                existing.pretreatment(),
+                existing.clinicalExamDate(),
+                existing.internalNote()
         ));
         return toDetail(saved);
     }
@@ -450,7 +515,10 @@ public class SampleService {
                 existing.completedAt(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                existing.pretreatment(),
+                existing.clinicalExamDate(),
+                existing.internalNote()
         ));
     }
 
@@ -478,7 +546,10 @@ public class SampleService {
                 existing.completedAt(),
                 existing.ownerAccountId(),
                 existing.createdByUserCode(),
-                existing.createdByDisplayName()
+                existing.createdByDisplayName(),
+                existing.pretreatment(),
+                existing.clinicalExamDate(),
+                existing.internalNote()
         ));
     }
 
@@ -643,7 +714,10 @@ public class SampleService {
                     sample.completedAt(),
                     resolvedAccountId,
                     sample.createdByUserCode(),
-                    sample.createdByDisplayName()
+                    sample.createdByDisplayName(),
+                    sample.pretreatment(),
+                    sample.clinicalExamDate(),
+                    sample.internalNote()
             ));
         }
     }
@@ -737,7 +811,10 @@ public class SampleService {
                 SampleWorkflowRules.canEditAnamnesis(sample),
                 SampleWorkflowRules.canEditAntibiogram(sample),
                 SampleWorkflowRules.canEditTherapy(sample),
-                sample.currentStep() == SampleWorkflowStep.COMPLETED
+                sample.currentStep() == SampleWorkflowStep.COMPLETED,
+                sample.pretreatment(),
+                sample.clinicalExamDate(),
+                sample.internalNote()
         );
     }
 
@@ -759,7 +836,15 @@ public class SampleService {
                 therapy.dryAntibioticKeys(),
                 therapy.dryAntibioticNames(),
                 therapy.farmerNote(),
-                therapy.internalNote()
+                therapy.internalNote(),
+                therapy.inUdderCount(),
+                therapy.inUdderDuration(),
+                therapy.systemicCount(),
+                therapy.systemicDuration(),
+                therapy.systemicDosage(),
+                therapy.systemicLocation(),
+                therapy.startvacVaccination() != null ? therapy.startvacVaccination() : Boolean.FALSE,
+                therapy.noAntibioticTreatment() != null ? therapy.noAntibioticTreatment() : Boolean.FALSE
         );
     }
 
@@ -877,7 +962,15 @@ public class SampleService {
             List<String> dryAntibioticKeys,
             List<String> dryAntibioticNames,
             String farmerNote,
-            String internalNote
+            String internalNote,
+            String inUdderCount,
+            String inUdderDuration,
+            String systemicCount,
+            String systemicDuration,
+            String systemicDosage,
+            String systemicLocation,
+            Boolean startvacVaccination,
+            Boolean noAntibioticTreatment
     ) {
     }
 
@@ -909,7 +1002,10 @@ public class SampleService {
             boolean anamnesisEditable,
             boolean antibiogramEditable,
             boolean therapyEditable,
-            boolean completed
+            boolean completed,
+            Pretreatment pretreatment,
+            LocalDate clinicalExamDate,
+            String internalNote
     ) {
     }
 
@@ -921,7 +1017,13 @@ public class SampleService {
             SamplingMode samplingMode,
             List<QuarterKey> flaggedQuarters,
             String userCode,
-            String userDisplayName
+            String userDisplayName,
+            String pretreatmentInUdderInjector,
+            String pretreatmentSystemicAntibiotics,
+            String pretreatmentPainMedication,
+            String pretreatmentDryOffTreatment,
+            String clinicalExamDate,
+            String internalNote
     ) {
     }
 
@@ -955,7 +1057,33 @@ public class SampleService {
             List<String> drySealerKeys,
             List<String> dryAntibioticKeys,
             String farmerNote,
-            String internalNote
+            String internalNote,
+            String inUdderCount,
+            String inUdderDuration,
+            String systemicCount,
+            String systemicDuration,
+            String systemicDosage,
+            String systemicLocation,
+            Boolean startvacVaccination,
+            Boolean noAntibioticTreatment
     ) {
     }
+
+    private LocalDate parseClinicalExamDate(String dateStr) {
+        if (dateStr == null || dateStr.isBlank()) {
+            return null;
+        }
+        try {
+            // Try ISO format first (YYYY-MM-DD)
+            return LocalDate.parse(dateStr);
+        } catch (DateTimeParseException e) {
+            try {
+                // Try German format (DD.MM.YYYY)
+                DateTimeFormatter formatter = DateTimeFormatter.ofPattern("dd.MM.yyyy");
+                return LocalDate.parse(dateStr, formatter);
+            } catch (DateTimeParseException e2) {
+                return null;
+            }
+        }
+    }
 }

backend/src/main/java/de/svencarstensen/muh/web/SampleController.java

@@ -54,7 +54,13 @@ public class SampleController {
                 request.samplingMode(),
                 request.flaggedQuarters(),
                 deriveUserLabel(user.displayName()),
-                user.displayName()
+                user.displayName(),
+                request.pretreatmentInUdderInjector(),
+                request.pretreatmentSystemicAntibiotics(),
+                request.pretreatmentPainMedication(),
+                request.pretreatmentDryOffTreatment(),
+                request.clinicalExamDate(),
+                request.internalNote()
         ));
     }
 

frontend/src/lib/types.ts

@@ -9,6 +9,13 @@ export type QuarterKey =
   | "LEFT_REAR"
   | "RIGHT_REAR";
 export type PathogenKind = "BACTERIAL" | "NO_GROWTH" | "CONTAMINATED" | "OTHER";
+
+export interface Pretreatment {
+  inUdderInjector: string | null;
+  systemicAntibiotics: string | null;
+  painMedication: string | null;
+  dryOffTreatment: string | null;
+}
 export type SensitivityResult = "SENSITIVE" | "INTERMEDIATE" | "RESISTANT";
 export type MedicationCategory =
   | "IN_UDDER"
@@ -145,6 +152,14 @@ export interface TherapyView {
   dryAntibioticNames: string[];
   farmerNote: string | null;
   internalNote: string | null;
+  inUdderCount: string | null;
+  inUdderDuration: string | null;
+  systemicCount: string | null;
+  systemicDuration: string | null;
+  systemicDosage: string | null;
+  systemicLocation: string | null;
+  startvacVaccination: boolean | null;
+  noAntibioticTreatment: boolean | null;
 }
 
 export interface SampleDetail {
@@ -176,6 +191,9 @@ export interface SampleDetail {
   antibiogramEditable: boolean;
   therapyEditable: boolean;
   completed: boolean;
+  pretreatment: Pretreatment | null;
+  clinicalExamDate: string | null;
+  internalNote: string | null;
 }
 
 export interface FarmerRow {

frontend/src/pages/AdminDashboardPage.tsx

@@ -7,6 +7,7 @@ import {
   Title,
   Tooltip,
   Legend,
+  type TooltipItem,
 } from "chart.js";
 import { Bar } from "react-chartjs-2";
 import { apiGet } from "../lib/api";
@@ -101,8 +102,9 @@ export default function AdminDashboardPage() {
           size: 13,
         },
         callbacks: {
-          label: (context: { parsed: { y: number } }) => {
+          label: (context: TooltipItem<"bar">) => {
-            return `${context.parsed.y} Proben`;
+            const value = context.parsed.y as number | null;
+            return `${value ?? 0} Proben`;
           },
         },
       },

frontend/src/pages/AnamnesisPage.tsx

@@ -1,12 +1,13 @@
 import { useEffect, useMemo, useState } from "react";
 import { useNavigate, useParams } from "react-router-dom";
 import { apiGet, apiPut } from "../lib/api";
-import type { ActiveCatalogSummary, QuarterKey, QuarterView, SampleDetail } from "../lib/types";
+import type { ActiveCatalogSummary, PathogenKind, QuarterKey, QuarterView, SampleDetail } from "../lib/types";
 
 type QuarterFormState = {
   pathogenBusinessKey: string;
   customPathogenName: string;
   cellCount: string;
+  pathogenKind: PathogenKind | null;
 };
 
 function quarterStateFromSample(sample: SampleDetail) {
@@ -15,11 +16,18 @@ function quarterStateFromSample(sample: SampleDetail) {
       pathogenBusinessKey: quarter.pathogenBusinessKey ?? "",
       customPathogenName: quarter.customPathogenName ?? "",
       cellCount: quarter.cellCount ? String(quarter.cellCount) : "",
+      pathogenKind: quarter.pathogenKind,
     };
     return accumulator;
   }, {});
 }
 
+// Special pathogen options like in Lua
+const SPECIAL_PATHOGENS = [
+  { key: "NO_GROWTH", label: "Kein bakterielles Wachstum", kind: "NO_GROWTH" as PathogenKind },
+  { key: "CONTAMINATED", label: "Verunreinigte Probe", kind: "CONTAMINATED" as PathogenKind },
+];
+
 export default function AnamnesisPage() {
   const { sampleId } = useParams();
   const navigate = useNavigate();
@@ -76,6 +84,20 @@ export default function AnamnesisPage() {
     return Boolean(quarterState?.pathogenBusinessKey || quarterState?.customPathogenName?.trim());
   }
 
+  function selectSpecialPathogen(quarterKey: QuarterKey, kind: PathogenKind) {
+    updateQuarter(quarterKey, {
+      pathogenBusinessKey: "",
+      customPathogenName: "",
+      pathogenKind: kind,
+    });
+  }
+
+  function isSpecialPathogenSelected(quarterKey: QuarterKey, kind: PathogenKind) {
+    return quarterStates[quarterKey]?.pathogenKind === kind && 
+           !quarterStates[quarterKey]?.pathogenBusinessKey &&
+           !quarterStates[quarterKey]?.customPathogenName;
+  }
+
   async function handleSave() {
     if (!sampleId || !sample) {
       return;
@@ -117,6 +139,7 @@ export default function AnamnesisPage() {
     pathogenBusinessKey: "",
     customPathogenName: "",
     cellCount: "",
+    pathogenKind: null,
   };
 
   return (
@@ -168,7 +191,25 @@ export default function AnamnesisPage() {
             <div className="info-chip">Auffaelliges Viertel markiert</div>
           ) : null}
 
-          <p className="required-label">Erreger</p>
+          {/* Special pathogen options like in Lua */}
+          <p className="required-label">Sonderfaelle</p>
+          <div className="pathogen-grid">
+            {SPECIAL_PATHOGENS.map((pathogen) => (
+              <button
+                key={pathogen.key}
+                type="button"
+                className={`pathogen-button ${
+                  isSpecialPathogenSelected(visibleQuarter.quarterKey, pathogen.kind) ? "is-selected" : ""
+                }`}
+                onClick={() => selectSpecialPathogen(visibleQuarter.quarterKey, pathogen.kind)}
+                disabled={!sample.anamnesisEditable}
+              >
+                <strong>{pathogen.label}</strong>
+              </button>
+            ))}
+          </div>
+
+          <p className="required-label section-card__spacer">Erreger (Katalog)</p>
           <div className={`pathogen-grid ${showValidation && !quarterHasPathogen(visibleQuarter.quarterKey) ? "is-invalid" : ""}`}>
             {catalogs.pathogens.map((pathogen) => (
               <button
@@ -181,6 +222,7 @@ export default function AnamnesisPage() {
                   updateQuarter(visibleQuarter.quarterKey, {
                     pathogenBusinessKey: pathogen.businessKey,
                     customPathogenName: "",
+                    pathogenKind: null,
                   })
                 }
                 disabled={!sample.anamnesisEditable}
@@ -199,6 +241,7 @@ export default function AnamnesisPage() {
                 updateQuarter(visibleQuarter.quarterKey, {
                   customPathogenName: event.target.value,
                   pathogenBusinessKey: "",
+                  pathogenKind: null,
                 })
               }
               disabled={!sample.anamnesisEditable}
@@ -221,8 +264,8 @@ export default function AnamnesisPage() {
           <div className="info-panel info-panel--spaced">
             <strong>Hinweis</strong>
             <p>
-              Kein Wachstum oder verunreinigte Proben werden später automatisch vom
+              Bei "Kein bakterielles Wachstum" oder "Verunreinigte Probe" wird das Antibiogramm
-              Antibiogramm ausgeschlossen.
+              übersprungen und direkt zur Therapie weitergeleitet.
             </p>
           </div>
         </article>

frontend/src/pages/AntibiogramPage.tsx

@@ -167,9 +167,9 @@ export default function AntibiogramPage() {
                 <thead>
                   <tr>
                     <th>Antibiotikum</th>
-                    <th>S</th>
+                    <th className="matrix-col">Sensibel</th>
-                    <th>I</th>
+                    <th className="matrix-col">Intermediär</th>
-                    <th>R</th>
+                    <th className="matrix-col">Resistent</th>
                   </tr>
                 </thead>
                 <tbody>
@@ -180,7 +180,7 @@ export default function AntibiogramPage() {
                         <small className="table-subtext">{antibiotic.code ?? "ANT"}</small>
                       </td>
                       {(["SENSITIVE", "INTERMEDIATE", "RESISTANT"] as SensitivityResult[]).map((result) => (
-                        <td key={result}>
+                        <td key={result} className="matrix-col">
                           <button
                             type="button"
                             className={`matrix-button ${
@@ -191,7 +191,7 @@ export default function AntibiogramPage() {
                             onClick={() => updateResult(group.referenceQuarter, antibiotic.businessKey, result)}
                             disabled={!sample.antibiogramEditable}
                           >
-                            {result === "SENSITIVE" ? "S" : result === "INTERMEDIATE" ? "I" : "R"}
+                            {result === "SENSITIVE" ? "Sensibel" : result === "INTERMEDIATE" ? "Intermediär" : "Resistent"}
                           </button>
                         </td>
                       ))}

frontend/src/pages/SampleRegistrationPage.tsx

@@ -18,6 +18,14 @@ const QUARTERS: { key: QuarterKey; label: string }[] = [
   { key: "RIGHT_REAR", label: "Hinten rechts" },
 ];
 
+// Pretreatment options from Lua version
+const PRETREATMENT_OPTIONS = [
+  { key: "inUdderInjector", label: "Euterinjektor" },
+  { key: "systemicAntibiotics", label: "Systemische Antibiotika" },
+  { key: "painMedication", label: "Schmerzmittel" },
+  { key: "dryOffTreatment", label: "Trockensteller" },
+];
+
 export default function SampleRegistrationPage() {
   const { sampleId } = useParams();
   const navigate = useNavigate();
@@ -32,6 +40,15 @@ export default function SampleRegistrationPage() {
   const [sampleKind, setSampleKind] = useState<SampleKind>("LACTATION");
   const [samplingMode, setSamplingMode] = useState<SamplingMode>("SINGLE_SITE");
   const [flaggedQuarters, setFlaggedQuarters] = useState<QuarterKey[]>([]);
+  // New fields from Lua version
+  const [pretreatment, setPretreatment] = useState<Record<string, string>>({
+    inUdderInjector: "",
+    systemicAntibiotics: "",
+    painMedication: "",
+    dryOffTreatment: "",
+  });
+  const [clinicalExamDate, setClinicalExamDate] = useState("");
+  const [internalNote, setInternalNote] = useState("");
   const [loading, setLoading] = useState(true);
   const [saving, setSaving] = useState(false);
   const [message, setMessage] = useState<string | null>(null);
@@ -55,6 +72,17 @@ export default function SampleRegistrationPage() {
           setFlaggedQuarters(
             sample.quarters.filter((quarter) => quarter.flagged).map((quarter) => quarter.quarterKey),
           );
+          // Load new fields
+          if (sample.pretreatment) {
+            setPretreatment({
+              inUdderInjector: sample.pretreatment.inUdderInjector ?? "",
+              systemicAntibiotics: sample.pretreatment.systemicAntibiotics ?? "",
+              painMedication: sample.pretreatment.painMedication ?? "",
+              dryOffTreatment: sample.pretreatment.dryOffTreatment ?? "",
+            });
+          }
+          setClinicalExamDate(sample.clinicalExamDate ?? "");
+          setInternalNote(sample.internalNote ?? "");
         } else {
           const dashboard = await apiGet<DashboardOverview>("/dashboard");
           setSampleNumber(dashboard.nextSampleNumber);
@@ -78,6 +106,13 @@ export default function SampleRegistrationPage() {
     );
   }
 
+  function updatePretreatment(key: string, value: string) {
+    setPretreatment((current) => ({
+      ...current,
+      [key]: value,
+    }));
+  }
+
   async function handleSubmit(event: FormEvent<HTMLFormElement>) {
     event.preventDefault();
     setShowValidation(true);
@@ -101,6 +136,13 @@ export default function SampleRegistrationPage() {
       flaggedQuarters,
       userCode: user.displayName,
       userDisplayName: user.displayName,
+      // New fields
+      pretreatmentInUdderInjector: pretreatment.inUdderInjector || null,
+      pretreatmentSystemicAntibiotics: pretreatment.systemicAntibiotics || null,
+      pretreatmentPainMedication: pretreatment.painMedication || null,
+      pretreatmentDryOffTreatment: pretreatment.dryOffTreatment || null,
+      clinicalExamDate: clinicalExamDate || null,
+      internalNote: internalNote || null,
     };
 
     try {
@@ -126,7 +168,7 @@ export default function SampleRegistrationPage() {
           <p className="eyebrow">Neuanlage</p>
           <h3>Probe {sampleNumber ?? "..."}</h3>
           <p className="muted-text">
-            Die Probenummer wird fortlaufend vergeben. Trockensteller lassen sich ueber den
+            Die Probenummer wird fortlaufend vergeben. Trockensteller lassen sich über den
             Schalter Trockenstellerprobe markieren.
           </p>
         </div>
@@ -258,6 +300,55 @@ export default function SampleRegistrationPage() {
         </section>
       ) : null}
 
+      {/* New section: Pretreatment from Lua version */}
+      <section className="section-card">
+        <p className="eyebrow">Vorbehandelt mit</p>
+        <div className="field-grid field-grid--stacked">
+          {PRETREATMENT_OPTIONS.map((option) => (
+            <label key={option.key} className="field">
+              <span>{option.label}</span>
+              <input
+                type="text"
+                value={pretreatment[option.key]}
+                onChange={(event) => updatePretreatment(option.key, event.target.value)}
+                disabled={!editable}
+                placeholder="Ohne Vorbehandlung"
+              />
+            </label>
+          ))}
+        </div>
+      </section>
+
+      {/* New section: Clinical Exam Date from Lua version */}
+      <section className="form-grid">
+        <article className="section-card">
+          <p className="eyebrow">Klinische Untersuchung</p>
+          <label className="field">
+            <span>Untersuchungsdatum (TT.MM.JJJJ)</span>
+            <input
+              type="text"
+              value={clinicalExamDate}
+              onChange={(event) => setClinicalExamDate(event.target.value)}
+              disabled={!editable}
+              placeholder="z.B. 15.03.2024"
+            />
+          </label>
+        </article>
+
+        <article className="section-card">
+          <p className="eyebrow">Interne Bemerkung</p>
+          <label className="field">
+            <span>Bemerkung zur Probe</span>
+            <textarea
+              value={internalNote}
+              onChange={(event) => setInternalNote(event.target.value)}
+              disabled={!editable}
+              rows={3}
+            />
+          </label>
+        </article>
+      </section>
+
       <div className="page-actions">
         <button type="submit" className="accent-button" disabled={saving || !editable}>
           {saving ? "Speichern ..." : "Speichern"}

frontend/src/pages/TherapyPage.tsx

@@ -11,6 +11,12 @@ function medicationOptions(catalogs: ActiveCatalogSummary, category: MedicationC
   return catalogs.medications.filter((medication) => medication.category === category);
 }
 
+// Options for dropdowns like in Lua version
+const COUNT_OPTIONS = ["1", "2", "3", "4", "5"];
+const DURATION_OPTIONS = ["1 Tag", "2 Tage", "3 Tage", "4 Tage", "5 Tage", "6 Tage", "7 Tage", "8 Tage", "10 Tage", "14 Tage"];
+const DOSAGE_OPTIONS = ["einmalig", "1 x", "2 x", "3 x"];
+const LOCATION_OPTIONS = ["i.m.", "i.v.", "s.c."];
+
 export default function TherapyPage() {
   const { sampleId } = useParams();
 
@@ -26,6 +32,15 @@ export default function TherapyPage() {
   const [dryAntibioticKeys, setDryAntibioticKeys] = useState<string[]>([]);
   const [farmerNote, setFarmerNote] = useState("");
   const [internalNote, setInternalNote] = useState("");
+  // New fields from Lua version
+  const [inUdderCount, setInUdderCount] = useState("");
+  const [inUdderDuration, setInUdderDuration] = useState("");
+  const [systemicCount, setSystemicCount] = useState("");
+  const [systemicDuration, setSystemicDuration] = useState("");
+  const [systemicDosage, setSystemicDosage] = useState("");
+  const [systemicLocation, setSystemicLocation] = useState("");
+  const [startvacVaccination, setStartvacVaccination] = useState(false);
+  const [noAntibioticTreatment, setNoAntibioticTreatment] = useState(false);
   const [message, setMessage] = useState<string | null>(null);
   const [saving, setSaving] = useState(false);
 
@@ -51,6 +66,15 @@ export default function TherapyPage() {
         setDryAntibioticKeys(sampleResponse.therapy?.dryAntibioticKeys ?? []);
         setFarmerNote(sampleResponse.therapy?.farmerNote ?? "");
         setInternalNote(sampleResponse.therapy?.internalNote ?? "");
+        // Load new fields
+        setInUdderCount(sampleResponse.therapy?.inUdderCount ?? "");
+        setInUdderDuration(sampleResponse.therapy?.inUdderDuration ?? "");
+        setSystemicCount(sampleResponse.therapy?.systemicCount ?? "");
+        setSystemicDuration(sampleResponse.therapy?.systemicDuration ?? "");
+        setSystemicDosage(sampleResponse.therapy?.systemicDosage ?? "");
+        setSystemicLocation(sampleResponse.therapy?.systemicLocation ?? "");
+        setStartvacVaccination(sampleResponse.therapy?.startvacVaccination ?? false);
+        setNoAntibioticTreatment(sampleResponse.therapy?.noAntibioticTreatment ?? false);
       } catch (loadError) {
         setMessage((loadError as Error).message);
       }
@@ -65,6 +89,14 @@ export default function TherapyPage() {
     setter(list.includes(value) ? list.filter((entry) => entry !== value) : [...list, value]);
   }
 
+  // Check if "Keine" (None) is selected for in-udder or systemic
+  const noInUdderSelected = inUdderMedicationKeys.some(key => 
+    catalogs?.medications.find(m => m.businessKey === key)?.name === "Keine"
+  );
+  const noSystemicSelected = systemicMedicationKeys.some(key => 
+    catalogs?.medications.find(m => m.businessKey === key)?.name === "Keine"
+  );
+
   async function handleSave() {
     if (!sampleId) {
       return;
@@ -83,6 +115,15 @@ export default function TherapyPage() {
         dryAntibioticKeys,
         farmerNote,
         internalNote,
+        // New fields
+        inUdderCount: inUdderCount || null,
+        inUdderDuration: inUdderDuration || null,
+        systemicCount: systemicCount || null,
+        systemicDuration: systemicDuration || null,
+        systemicDosage: systemicDosage || null,
+        systemicLocation: systemicLocation || null,
+        startvacVaccination,
+        noAntibioticTreatment,
       });
       setSample(response);
       setMessage(response.completed ? "Probe gespeichert und abgeschlossen." : "Aenderung gespeichert.");
@@ -168,7 +209,35 @@ export default function TherapyPage() {
               ))}
             </div>
 
+            {/* In-Udder Details from Lua */}
+            {!noInUdderSelected && inUdderMedicationKeys.length > 0 && (
+              <div className="field-grid field-grid--2col section-card__spacer">
                 <label className="field">
+                  <span>Anzahl</span>
+                  <select
+                    value={inUdderCount}
+                    onChange={(e) => setInUdderCount(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {COUNT_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+                <label className="field">
+                  <span>Dauer</span>
+                  <select
+                    value={inUdderDuration}
+                    onChange={(e) => setInUdderDuration(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {DURATION_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+              </div>
+            )}
+
+            <label className="field section-card__spacer">
               <span>Sonstiges</span>
               <textarea
                 value={inUdderOther}
@@ -202,7 +271,57 @@ export default function TherapyPage() {
               )}
             </div>
 
+            {/* Systemic Details from Lua */}
+            {!noSystemicSelected && systemicMedicationKeys.length > 0 && (
+              <div className="field-grid field-grid--2col section-card__spacer">
                 <label className="field">
+                  <span>Anzahl</span>
+                  <select
+                    value={systemicCount}
+                    onChange={(e) => setSystemicCount(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {COUNT_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+                <label className="field">
+                  <span>Dauer</span>
+                  <select
+                    value={systemicDuration}
+                    onChange={(e) => setSystemicDuration(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {DURATION_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+                <label className="field">
+                  <span>Dosierung</span>
+                  <select
+                    value={systemicDosage}
+                    onChange={(e) => setSystemicDosage(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {DOSAGE_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+                <label className="field">
+                  <span>Ort</span>
+                  <select
+                    value={systemicLocation}
+                    onChange={(e) => setSystemicLocation(e.target.value)}
+                    disabled={therapyLocked}
+                  >
+                    <option value="">-</option>
+                    {LOCATION_OPTIONS.map(opt => <option key={opt} value={opt}>{opt}</option>)}
+                  </select>
+                </label>
+              </div>
+            )}
+
+            <label className="field section-card__spacer">
               <span>Sonstiges</span>
               <textarea
                 value={systemicOther}
@@ -254,6 +373,33 @@ export default function TherapyPage() {
         </section>
       )}
 
+      {/* Additional Options from Lua */}
+      {sample.sampleKind === "LACTATION" && (
+        <section className="section-card">
+          <p className="eyebrow">Sonstiges</p>
+          <div className="field-grid">
+            <label className="field field--checkbox">
+              <input
+                type="checkbox"
+                checked={noAntibioticTreatment}
+                onChange={(e) => setNoAntibioticTreatment(e.target.checked)}
+                disabled={therapyLocked}
+              />
+              <span>Keine Antibiose, gut ausmelken (evtl. Oxytocin), als letzte melken, strikte Hygiene</span>
+            </label>
+            <label className="field field--checkbox">
+              <input
+                type="checkbox"
+                checked={startvacVaccination}
+                onChange={(e) => setStartvacVaccination(e.target.checked)}
+                disabled={therapyLocked}
+              />
+              <span>Startvac-Impfung</span>
+            </label>
+          </div>
+        </section>
+      )}
+
       <section className="form-grid">
         <article className="section-card">
           <label className="field">

frontend/src/styles/global.css

@@ -624,10 +624,17 @@ a {
 }
 
 .matrix-button {
-  width: 42px;
+  min-width: 90px;
+  width: auto;
   height: 42px;
+  padding: 0 16px;
   border-radius: 12px;
   background: rgba(255, 255, 255, 0.8);
+  white-space: nowrap;
+}
+
+.matrix-col {
+  text-align: center !important;
 }
 
 .eye-button {
@@ -1489,3 +1496,71 @@ a {
     height: 72vh;
   }
 }
+
+/* Additional styles for new Lua features */
+
+/* Checkbox field styling */
+.field--checkbox {
+  display: flex;
+  flex-direction: row;
+  align-items: flex-start;
+  gap: 12px;
+}
+
+.field--checkbox input[type="checkbox"] {
+  width: 20px;
+  height: 20px;
+  margin-top: 2px;
+  flex-shrink: 0;
+  accent-color: var(--accent);
+}
+
+.field--checkbox span {
+  font-size: 0.9rem;
+  color: var(--text);
+  line-height: 1.5;
+}
+
+/* Special pathogen buttons (NO_GROWTH, CONTAMINATED) */
+.pathogen-button.special-pathogen {
+  background: rgba(138, 101, 0, 0.1);
+  border: 1px solid rgba(138, 101, 0, 0.2);
+}
+
+.pathogen-button.special-pathogen.is-selected {
+  background: linear-gradient(135deg, rgba(138, 101, 0, 0.25), rgba(138, 101, 0, 0.1));
+  box-shadow: inset 0 0 0 1px rgba(138, 101, 0, 0.4);
+}
+
+/* Therapy detail fields */
+.field-grid--2col {
+  grid-template-columns: repeat(2, minmax(0, 1fr));
+}
+
+@media (max-width: 640px) {
+  .field-grid--2col {
+    grid-template-columns: 1fr;
+  }
+}
+
+/* Disabled state for therapy when "Keine" is selected */
+.choice-chip:disabled,
+.field input:disabled,
+.field select:disabled,
+.field textarea:disabled {
+  opacity: 0.6;
+  cursor: not-allowed;
+}
+
+/* Pretreatment section styling */
+.pretreatment-grid {
+  display: grid;
+  gap: 16px;
+  grid-template-columns: repeat(2, minmax(0, 1fr));
+}
+
+@media (max-width: 640px) {
+  .pretreatment-grid {
+    grid-template-columns: 1fr;
+  }
+}